Tack It Down Frame as usual, using powder-actuated gun-driven fasteners to pin wood to concrete temporarily as needed.
Drill Precisely With the framing complete, mark the locations for the code-required anchors or engineer-specified hold-downs. Drill a slightly oversize hole through the wood and into the concrete at each required location.
Apply the Epoxy Use a special epoxy canister in a caulking gun with an elongated mixing nozzle to inject epoxy into each hole, inserting the appropriate threaded rod as you go. Temporarily attach plate washers and nuts, but don't tighten them yet.