MarketWatch's Catey Hill sifts through data released Wednesday by the Economic Policy Institute which looked at the cost of living in 618 metros through a family filter, factoring in child care, food, transportation, housing, health care and related expenses like school supplies and clothing for a two-child household. 

For most of the nation's families (500 of the 681 cities), child care is the No. 1 line item, averaging about $12,500 a year nationally. The research found that in some pockets of the country, being a parent means you have to make six figures just to keep your head above water. 

So, where does it cost the most to raise two children? Washington, D.C., is the nation's capital of child-care expenses, where a family of four needs just over $106,000 to get by. It was followed by Long Island, N.Y. (Nassau and Suffolk Counties), Westchester County, N.Y., New York City, and Stamford-Norwalk, Conn.

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